Genomic signatures of the evolution of defence against its natural enemies in the poisonous and medicinal plant Datura stramonium (Solanaceae)

Journal article

I. De-la-Cruz, A. Hallab, U. Olivares-Pinto, R. Tapia-López, S. Velázquez-Márquez, D. Piñero, K. Oyama, B. Usadel, J. Núñez‐Farfán
Scientific Reports, 2021

Semantic Scholar DOI PubMedCentral PubMed

Cite

APA Click to copy
De-la-Cruz, I., Hallab, A., Olivares-Pinto, U., Tapia-López R., Velázquez-Márquez, S., Piñero, D., … Núñez‐Farfán, J. (2021). Genomic signatures of the evolution of defence against its natural enemies in the poisonous and medicinal plant Datura stramonium (Solanaceae). Scientific Reports.

Chicago/Turabian Click to copy
De-la-Cruz, I., A. Hallab, U. Olivares-Pinto, Tapia-López R., S. Velázquez-Márquez, D. Piñero, K. Oyama, B. Usadel, and J. Núñez‐Farfán. “Genomic Signatures of the Evolution of Defence against Its Natural Enemies in the Poisonous and Medicinal Plant Datura Stramonium (Solanaceae).” Scientific Reports (2021).

MLA Click to copy
De-la-Cruz, I., et al. “Genomic Signatures of the Evolution of Defence against Its Natural Enemies in the Poisonous and Medicinal Plant Datura Stramonium (Solanaceae).” Scientific Reports, 2021.

BibTeX Click to copy

@article{i2021a,
  title = {Genomic signatures of the evolution of defence against its natural enemies in the poisonous and medicinal plant Datura stramonium (Solanaceae)},
  year = {2021},
  journal = {Scientific Reports},
  author = {De-la-Cruz, I. and Hallab, A. and Olivares-Pinto, U. and Tapia-López, R. and Velázquez-Márquez, S. and Piñero, D. and Oyama, K. and Usadel, B. and Núñez‐Farfán, J.}
}

Abstract

Tropane alkaloids and terpenoids are widely used in the medicine and pharmaceutic industry and evolved as chemical defenses against herbivores and pathogens in the annual herb Datura stramonium (Solanaceae). Here, we present the first draft genomes of two plants from contrasting environments of D. stramonium . Using these de novo assemblies, along with other previously published genomes from 11 Solanaceae species, we carried out comparative genomic analyses to provide insights on the genome evolution of D. stramonium within the Solanaceae family, and to elucidate adaptive genomic signatures to biotic and abiotic stresses in this plant. We also studied, in detail, the evolution of four genes of D. stramonium —Putrescine N -methyltransferase, Tropinone reductase I, Tropinone reductase II and Hyoscyamine-6S-dioxygenase—involved in the tropane alkaloid biosynthesis. Our analyses revealed that the genomes of D. stramonium show signatures of expansion, physicochemical divergence and/or positive selection on proteins related to the production of tropane alkaloids, terpenoids, and glycoalkaloids as well as on R defensive genes and other important proteins related with biotic and abiotic pressures such as defense against natural enemies and drought.